Lamivudine – Analyticsstanza

Lamivudine 5-Epimer:

4-Amino-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl] pyrimidin-2(1H)-one ; CAS : 139757-68-9 ; C8H11N3O3S ; MW: 229.26 ;

Lamivudine:

4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl] pyrimidin-2(1H)-one ; CAS : 134678-17-4 ; C8H11N3O3S ; MW: 229.26 ;

Lamivudine Impurity A :

Lamivudine Carboxylic Impurity ; (2R,5S)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylic acid ; CAS : 173829-09-9 ; C8H9N3O4S ; MW: 243.24

Lamivudine Impurity B :

4-Amino-1-[(2S,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one ; CAS : 136846-20-3 ;C8H11N3O3S ; MW: 229.26 ;

Lamivudine Impurity C :

2-Hydroxybenzenecarboxylic acid ; CAS : 69-72-7 ;

C7H6O3 ; MW: 138.12 ;

Lamivudine Impurity D:

Lamivudine Enantiomer ; 4-Amino-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one ; CAS : 134680-32-3 ; C8H11N3O3S ; MW: 229.26 ;

Lamivudine Impurity E:

Cytosine ; 4-Aminopyrimidin-2(1H)-one ; CAS : 71-30-7 ; C4H5N3O ; MW: 111.1 ;

Lamivudine Impurity F :

Pyrimidine-2,4(1H,3H)-dione ; CAS : 66-22-8 ; C4H4N2O2 ; MW: 112.09 ;

Lamivudine Impurity G:

Lamivudine (3S)-Sulfoxide ;

4-Amino-1-[(2R,3S,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl] pyrimidin-2(1H)-one S-oxide ; CAS : 160552-55-6 ; C8H11N3O4S ; MW: 245.26 ;

Lamivudine Impurity H :

Lamivudine (3R)-Sulfoxide ; 4-Amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl] pyrimidin-2(1H)-one S-oxide ; CAS : 160552-54-5 ; C8H11N3O4S ; MW: 245.26 ;

Lamivudine Impurity I:

Lamivudine Dioxolan Impurity ; 4-Amino-1-[(2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl] pyrimidin-2(1H)-one ; C8H11N3O4 ; MW: 213.19 ;

Lamivudine Impurity J:

Lamivudine Dione Impurity ; 1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidine-2,4(1H,3H)-dione ; CAS : 145986-07-8 ; C8H10N2O4S ; MW: 230.24 ;

Lamivudine Sulfoxide:

4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl] pyrimidin-2(1H)-one S-oxide ; CAS : 1235712-40-9 ; C8H11N3O4S ; MW: 245.26 ;

Lamivudine Uracil Derivative:

2,4(1H,3H)-Pyrimidinedione, 2,4-Dihydroxypyrimidine, 2,4-Pyrimidinediol; C8H10N2O4S; MW: 230.24 ;

Lamivudine S-Sulfoxide:

Lamivudine (S)-S-Oxide; 4-Amino-1-[(2R,3S,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone;
[2R-(2α,3α,5α)]-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone S-Oxide; 1,3-Oxathiolane, 2(1H)-pyrimidinone Deriv.; [2R-(2α,3α,5α)]-4-Amino-1-[2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone;
CAS Number:160552-55-6; C₈H₁₁N₃O₄S ; MW: 245.26 ;

Lamivudine R-Sulfoxide:

Lamivudine (R)-S-Oxide; 4-Amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone;
[2R-(2α,3β,5α)]-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone S-Oxide; 1,3-Oxathiolane, 2(1H)-pyrimidinone Deriv.; [2R-(2α,3β,5α)]-4-Amino-1-[2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone;
CAS Number:160552-54-5; C₈H₁₁N₃O₄S; MW: 245.26 ;

Lamividine Enatiomer:

4-Amino-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone;
(2S-cis)-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone;
(+)-BCH 189; 2’,3’-Dideoxy-3’-thiacytidine; 2’-Deoxy-3’-thiacytidine; C₈H₁₁N₃O₃S ; MW: 229.26 ;