Ramipril

Ramipril EP Impurity A Ramipril Impurity A :

(2S,3aS,6aS)-1-[(S)-2-[[(S)-1-(Methoxycarbonyl)-3-phenylpropyl]amino]propanoly]octahydrocyclopenta[b]pyrrole-2-carboxylic acid ;

C22H30N2O5 ; MW: 402.48 ;
Ramipril EP Impurity B Ramipril Impurity B:

(2S,3aS,6aS)-1-[(S)-2-[[(S)-1-[(methylethoxy)carbonyl]-3-phenylpropyl]amino] propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid ;

CAS :  295328-72-2 ; C24H34N2O5 ; MW: 430.54 ;
Ramipril EP Impurity C Ramipril Impurity C:

(2S,3aS,6aS)-1-[(S)-2-[[(S)-1-(Ethoxycarbonyl)-3-cyclohexylpropyl]amino]propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid hydrochloride ;

CAS : 99742-35-5 ; C23H39ClN2O5 ; MW: 459.02 ;
Ramipril EP Impurity D Ramipril Impurity D:

Ethyl (2S)-2-[(3S,5aS,8aS,9aS)-3-methyl-1,4-dioxodecahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-2-yl]-4-phenyl butanoate ; CAS : 108731-95-9 ; C23H30N2O4 ; MW: 398.50 ;
Ramipril EP Impurity E Ramipril Impurity E:

(2S,3aS,6aS)-1-[(S)-2-[[(S)-1-carboxy-3-phenylpropyl]amino]propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid disodium salt ;

CAS : 87269-97-4 (acid) ; C21H28N2O5 (acid) ; MW: 388.46 ; C21H26N2Na2O5 (disodium salt) ; MW: 388.46 ;
Ramipril EP Impurity F Ramipril Impurity F:

N-[(S)-(+)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanine (“ECPPA”) ;

CAS : 82717-96-2 ; C15H21NO4 ; MW: 279.33 ;
Ramipril EP Impurity H Ramipril  Impurity H:

2S,3aS,6aS)-1-[(R)-2-[[(S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid ;

(1R)-Ramipril ; Ramipril 1-Epimer ; CAS : 104195-90-6 ; C23H32N2O5 ; MW: 416.51 ;
Ramipril EP Impurity I Ramipril Impurity I:

(2S,3aS,6aS)-1-[(S)-2-[[(R)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid ; C23H32N2O5 ; MW: 416.51 ;
Ramipril EP Impurity J Ramipril Impurity J:

(2R,3aR,6aR)-1-[(R)-2-[[(R)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]propanoyl] octahydrocyclo penta [b] pyrrole-2-carboxylic acid ; CAS : 1246253-05-3 ; C23H32N2O5 ; MW: 416.51 ;
Ramipril EP Impurity K Ramipril  Impurity K :

(2S)-2-[(3S,5aS,8aS,9aS)-3-Methyl-1,4-dioxodecahydro-2H-cyclopenta[4,5] pyrrolo[1,2-a]pyrazin-2-yl]-4-phenylbutanoic acid ; CAS : 108736-10-3 ; C21H26N2O4 ; MW: 370.44 ;
Ramipril EP Impurity L Ramipril Impurity L:

Ethyl (2S)-2-[(3S,5aS,8aS,9aS)-9a-hydroxy-3-methyl-1,4-dioxodecahydro-2H-cyclopenta[4,5]pyrrolo [1,2-a]pyrazin-2-yl]-4-phenylbutanoate ; C23H30N2O5 ;MW: 414.49 ;
Ramipril EP Impurity M Ramipril Impurity M:

(2R,3R)-2,3-Di(benzoyloxy)butanedioic acid ; CAS :  2743-38-6 ; C18H14O8 ; MW: 358.30 ;
Ramipril EP Impurity N Ramipril Impurity N :

(2R,3aR,6aR)-1-[(S)-2-[[(S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]propanoyl]octahydrocyclopenta [b] pyrrole-2-carboxylic acid ; CAS : 129939-63-5 ; C23H32N2O5 ; Mol. Wt.: 416.51 ;
Ramipril EP Impurity O Ramipril  Impurity O:

Diethyl 2,2′-(2,5-dimethyl-3,6-dioxopiperazine-1,4-diyl)bis(4-phenylbutanoate) ;

C30H38N2O6 ; MW: 522.63 ;