Ritonavir

Ritonavir Ritonavir:

Thiazol-5-yl-methyl [(1S,2S,4S)-1-benzyl-2-hydroxy-4[[(2S)-3-methyl-2-[[methyl[[2-(1-methylethyl)thiazol-4-yl]methyl]carbamoyl]amino]butanoyl ]amino]-5-phenylpentyl]carbamate ; CAS : 155213-67-5 ; C37H48N6O5S2 ;

MW: 720.94 ;
Ritonavir EP Impurity A Ritonavir Impurity A:

(2S)-3-Methyl-2-[[methyl[[2-(1-methylethyl)thiazol-4-yl]methyl]carbamoyl] amino]butanoicacid ; CAS : 154212-61-0 ; C14H23N3O3S ; MW: 313.42 ;
Ritonavir EP Impurity B Ritonavir Impurity B:

 Thiazol-5-yl-methyl [(1S,2S,4S)-4-[[(2S)-2-amino-3-methylbutanoyl]amino]-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate ; CAS : 165315-97-9 (HCl salt) ; 765875-58-9 (base) ; C28H36N4O4S ; MW: 524.67 ;
Ritonavir EP Impurity C Ritonavir Impurity C :

Thiazol-5-yl-methyl [(1S,2S,4S)-4-(acetylamino)-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate ; CAS : 1010808-43-1 ;  C25H29N3O4S ; MW: 467.58 ;
Ritonavir EP Impurity D Ritonavir Impurity D :

Thiazol-5-yl-methyl [(1S,2S,4S)-1-benzyl-2-hydroxy-5-phenyl-4-[[(thiazol-5-yl-methoxy)carbonyl]amino]pentyl]carbamate ; C28H30N4O5S2 ; MW: 566.69 ;
Ritonavir EP Impurity E Ritonavir Impurity E:

Thiazol-5-yl-methyl [(1S,2S,4S)-1-benzyl-2-hydroxy-4-[[(2S)-2-[[[[2-(1-hydroxy-1-methylethyl)thiazol-4-yl]methyl]methylcarbamoyl]amino]-3-methylbutanoyl]amino]-5-phenylpentyl]carbamate ; CAS : 176655-56-4 ; C37H48N6O6S2 ; MW: 736.94  ;
Ritonavir EP Impurity F Ritonavir Impurity F:

 Thiazol-5-yl-methyl [(1S,2S,4S)-1-benzyl-4-[[(2S)-1-benzyl-2-hydroxy-4-[(4S)-4-(1-methylethyl)-2,5-dioxoimidazolidin-1-yl]-5-phenylpentyl]carbamate ; CAS : 1010809-61-6 ; C29H34N4O5S ; MW: 550.67 ;
Ritonavir EP Impurity G Ritonavir Impurity G:

 Thiazol-5-yl-methyl [(1S,2S,4S)-1-benzyl-4-[[(2S)-2-[[[[2-(1-hydroperoxy-1-methylethyl)thiazol-4-yl]methyl]methylcarbamoyl]amino]-3-methylbutanoyl] amino]-2-hydroxy-5-phenylpentyl]carbamate ;

C37H48N6O7S2 ; MW: 752.94 ;
Ritonavir EP Impurity H Ritonavir Impurity H:

Des-Isopropylthiazolyl Hydantoin-Oxazolidinone Ritonavir ; CAS : 1010809-43-4 ;

C30H32N4O6S ; MW: 576.66 ;
Ritonavir EP Impurity I Ritonavir Impurity I :

Thiazol-5-yl-methyl [((1S,2S,4S)-1-benzyl-4[[(2S)-2-[[[[2-ethylthiazol-4-yl]methyl]methylcarbamoyl]amino]-3-methylbutanoyl]amino]-2-hydroxy-5-phenylpentyl]carbamate ; CAS : 165315-26-4 ; C36H46N6O5S2 ;

MW: 706.92 ;
Ritonavir EP Impurity J Ritonavir Impurity J :

Thiazol-5-yl-methyl [(1S,2S,4S)-1-benzyl4-[[(1,1-dimethylethoxy)carbonyl] amino]-2-hydroxy-5-phenylpentyl]carbamate ; CAS : 162849-95-8 ; C28H35N3O5S ; MW: 525.66 ;
Ritonavir EP Impurity K Ritonavir Impurity K:

Thiazol-5-yl-methyl (1S,2S,4S)-1-benzyl-2-hydroxy-4-[[(2-methylpropoxy) carbonyl] amino]-5-phenylpentyl]carbamate ; C28H35N3O5S ; MW: 525.66 ;
Ritonavir EP Impurity L Ritonavir Impurity L:

 Desthiazolylmethyl Ritonavir ; (4S,5S)-4-benzyl-5-[(2S)-2-[[(2S)-3-methyl-2-[[methyl[[2(1-methylethyl) thiazol-4-yl]methyl]carbamoyl]amino]butanoyl]amino]-3-phenylpropyl] oxazolidin-2-one ;

CAS : 256328-82-2 ; C33H43N5O4S ; MW: 605.79 ;
Ritonavir EP Impurity M Ritonavir Impurity M:

2-Methylpropyl (2S)-3-methyl-2-[[methyl[[2-(1-methylethyl)thiazol-4-yl]methyl]carbamoyl]amino]butanoate ; C18H31N3O3S ; MW: 369.52 ;
Ritonavir EP Impurity N Ritonavir Impurity N:

Thiazol-5-yl-methyl [(1S,3S,4S)-1-benzyl-3-hydroxy-4-[[(2S)-3-methyl-2-[[methyl[[2-(1-methylethyl)thiazol-4-yl]methyl]carbamoyl]amino]butanoyl] amino]-5-phenylpentyl]carbamate ; CAS : 202816-62-4 ; C37H48N6O5S2 ;

MW: 720.94 ;
Ritonavir EP Impurity O Ritonavir Impurity O:

Thiazol-5-yl-methyl [(1S,2R,4S)-1-benzyl-2-hydroxy-4-[[(2S)-3-methyl-2-[[methyl[[2-(1-methylethyl)thiazol-4-yl]methyl]carbamoyl]amino]butanoyl] amino]-5-phenylpentyl]carbamate ; CAS : 1414933-81-5 ;  C37H48N6O5S2 ;

MW: 720.94 ;
Ritonavir EP Impurity P Ritonavir Impurity P:

Bis(thiazol-5-yl-methyl)[carbonylbis[imino[(2S,3S,5S)-3-hydroxy-1,6-diphenylhexane-5,2-diyl]]]dicarbamate ; C47H52N6O7S2 ; MW: 877.08 ;
Ritonavir EP Impurity Q Ritonavir Impurity Q :

Thiazol-5-yl-methyl [(1S,2R,4R)-1-benzyl-2-hydroxy-4-[[(2S)-3-methyl-2-[[methyl[[2-(1-methylethyl)thiazol-4-yl]methyl]carbamoyl]amino]butanoyl] amino]-5-phenylpentyl]carbamate ; C37H48N6O5S2 ; MW: 720.94 ;
Ritonavir EP Impurity R Ritonavir  Impurity R:

Thiazol-5-yl-methyl [(1S,2S,4R)-1-benzyl-2-hydroxy-4-[[(2S)-3-methyl-2-[[methyl[[2-(1-methylethyl)thiazol-4-yl]methyl]carbamoyl]amino]butanoyl] amino]-5-phenylpentyl]carbamate ;

C37H48N6O5S2 ; MW: 720.94 ;
Ritonavir EP Impurity S Ritonavir Impurity S:

Thiazol-5-yl-methyl [(1S,2S,4S)-1-benzyl-4-[[(2S)-2[[[(1S,3S,4S)-1-benzyl-3-hydroxy-5-phenyl-4-[[(thiazol-5-ylmethoxy)carbonyl]amino]pentyl]carbamoyl] amino]-3-methylbutanoyl]amino]-2-hydroxy-5-phenylpentyl]carbamate ; C52H61N7O8S2 ; MW: 976.21 ;
Ritonavir EP Impurity T Ritonavir Impurity T:

 (2S)-N-[(1S,2S,4S)-1-benzyl-2-hydroxy-4-[[(2S)3-methyl-2-[[methyl[[2-(1-methylethyl)thiazol-4yl]methyl]carbamoyl]amino]butanoyl]amino]-5-phenylpentyl]-3-methyl-2-[[methyl[[2-(1-methylethyl)thiazol-4-yl]methyl] carbamoyl]amino]butanamide ; CAS : 869368-48-9 ; C46H66N8O5S2 ; MW: 875.2 ;
Ritonavir EP Impurity U Ritonavir Impurity U:

 (1S,3S)-3-[[(2S)-3-methyl-2-[[methyl[[2-(1methylethyl)thiazol-4-yl] methyl] carbamoyl]amino]butanoyl]amino]-4-phenyl-1-[(1S)-2-phenyl-1-[[(thiazol-5-ylmethoxy)carbonyl]amino]ethyl]butyl (2S)-3-methyl-2-[[methyl[[2-(1-methyl ethyl)thiazol-4-yl]methyl]carbamoyl]amino]butanoate ; C51H69N9O7S3 ; MW: 1016.34 ;