Sitagliptin

Sitagliptin 2-Desfluoro Impurity Sitagliptin 2-Desfluoro Impurity:

(R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(4,5-difluorophenyl)butan-2-amine ; C16H16F5N5O ; MW: 389.32 ;
Sitagliptin Desfluorobenzene Analog Sitagliptin Desfluorobenzene Analog :

(R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-phenylbutan-2-amine ; C16H18F3N5O ; Mol. Wt.: 353.34 ;
Sitagliptin Enamine Impurity Sitagliptin Enamine Impurity  :

(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine ; CAS : 767340-03-4 ; C16H13F6N5O ; MW: 405.30 ;
Sitagliptin Impurity A Sitagliptin  Impurity A :

Sitagliptin (S)-Isomer Phosphate Salt ; CAS : 823817-58-9 ; C16H18F6N5O5P ; MW: 505.31 ;
Sitagliptin Impurity B Sitagliptin Impurity B :

4-Desfluoro Sitagliptin ; CAS : 1345822-87-8 ; C16H16F5N5O ; MW: 389.32 ;
Sitagliptin Impurity C Sitagliptin  Impurity C:

5-Desfluoro Sitagliptin ; CAS : 1345822-86-7 ; C16H16F5N5O ; MW: 389.32 ;
 
Sitagliptin Hydroxy Amide Impurity Sitagliptin Hydroxy Amide Impurity:

3-Hydroxy-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one ; C16H14F6N4O2 ; MW: 408.3 ;
Sitagliptin Ketoamide Impurity Sitagliptin Ketoamide Impurity :

(2Z)-4-Oxo-4-[3-(trifluoroMethyl)-5,6-dihydro-[1,2,4] triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one ; CAS : 764667-65-4 ; C16H12F6N4O2 ; MW: 406.28 ;
Sitagliptin N-Acetyl Impurity Sitagliptin N-Acetyl Impurity:

7-[(3R)-3-[(N-Acetyl)amino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine ; CAS : 1379666-94-0 ; C18H17F6N5O2 ; MW: 449.35 ;
Sitagliptin Phosphate Hydrate Sitagliptin Phosphate Hydrate:

(R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine phosphate hydrate ; CAS : 654671-77-9 ;  C16H15F6N5O (base) ; MW: 407.31 ;

C16H20F6N5O6P (phosphate hydrate) ; MW: 523.32 ;
Sitagliptin Triazole Hydrochloride Sitagliptin Triazole Hydrochloride:

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride ; CAS : 762240-92-6 ; C6H8ClF3N4 ;MW: 228.60 ;
Sitagliptin FP Impurity A Sitagliptin FP Impurity A:

N-[(2R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-yl]aspartic acid ;  C20H19F6N5O5 ; MW: 523.39 ;
Sitagliptin FP Impurity B Sitagliptin FP Impurity B :

10-(2,4,5-Trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro [1,2,4] triazolo [3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione ; C16H13F6N5O2 ; MW: 421.3 ;
Sitagliptin FP Impurity C Sitagliptin FP Impurity C :

(3E)-1-[3-(Trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)but-3-en-1-one ; C16H12F6N4O ; MW: 390.28 ;
Sitagliptin FP Impurity D Sitagliptin FP Impurity D:

3-Desamino-2,3-Dehydro Sitagliptin ; CAS : 1253056-18-6 ;

C16H12F6N4O ; MW: 390.28 ;
Sitagliptin FP Impurity E Sitagliptin FP Impurity E:

(3R-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid ; CAS : 936630-57-8 ;  C10H10F3NO2 ; MW: 233.19 ;