Sofosbuvir (2R)-Methyl Impurity :
Isopropyl (2R)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-yl]methoxy-phenoxy-phosphoryl] amino] propanoate ; CAS : 1190308-01-0 ; C22H29FN3O9P ; MW: 529.46. |
Sofosbuvir :
Isopropyl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-yl]methoxy-phenoxy-phosphoryl] amino] propanoate ; CAS : 1190307-88-0 ; C22H29FN3O9P ;MW: 529.45 ; |
Sofosbuvir alpha-Isomer:
Isopropyl (2S)-2-[[[(2R,3R,4R,5S)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-yl]methoxy-phenoxy-phosphoryl] amino] propanoate ; C22H29FN3O9P ; MW: 529.45 ; |
Sofosbuvir Desphosphate alpha-Isomer:
[(2R,3R,4R,5S)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-yl]methanol ; C10H13FN2O5 ;MW: 260.22 ; |
Sofosbuvir Desphosphate Impurity :
[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-yl]methanol ; C10H13FN2O5 ; MW: 260.22 ; |
Sofosbuvir O-Desisopropyl Impurity:
(2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-Dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-yl]methoxy-phenoxy-phosphoryl] amino] propanoic acid ; C19H23FN3O9P ; MW: 487.37 ; |
Sofosbuvir O-Desisopropyl O-Desphenyl Impurity :
(2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-Dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] amino] propanoic acid ; CAS : 1233335-78-8 ; C13H19FN3O9P ; MW: 411.28 ; |
Sofosbuvir O-Desphenyl Impurity :
Isopropyl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] amino] propanoate ; C16H25FN3O9P ; MW: 453.36 ; |
Sofosbuvir Phosphate Impurity :
Isopropyl N-(Hydroxyphenoxyphosphinyl)alaninate sodium salt ; CAS : 1520010-86-9 (acid) ; C12H17NNaO5P ; MW: 309.23 ; |
Sofosbuvir Phosphoric Acid Impurity :
((2R,3S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-yl)methyl dihydrogen phosphate ; C10H14FN2O8P ; MW: 340.2 ; |